New Insights on the Molecular Drivers of IL-23 Blockade in Psoriasis
A high-resolution spatial and transcriptomic atlas of IL-23 blockade in skin provides new insights on treatment response and resistance in psoriasis patients. Psoriasis vulgaris and other chronic inflammatory diseases improve markedly with therapeutic blockade of IL-23 signaling, but the genetic mechanisms underlying clinical responses remain poorly understood. The study, which was led by Enable Medicine […]